Further Information
Serine/threonine-protein kinase PLK2, Polo-like kinase 2, PLK-2, hPlk2, Serine/threonine-protein kinase SNK, hSNK, Serum-inducible kinase, PLK2, SNK
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Plks (polo-like kinases) encode serine/threonine kinases that are closely
related to polo and CDC5, genes that are required for passage through mitosis
in Drosophila and Saccharomyces, respectively. Polo-like kinases, which
include Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk
(for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cell
proliferation. Plk protein accumulates in the cell during S and G2 phases of
the cell cycle, and both protein content and catalytic activity peak at the
onset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk are
immediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.
- Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
- Liby, K., et al., DNA Seq. 11:527-533 (2001).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This PLK2 (SNK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-406 amino acids from the C-terminal region of human PLK2 (SNK).
10769
Serine/threonine-protein kinase PLK2
PLK2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
78 kDa
Q9NYY3
22096374
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Signal Transduction
Q9NYY3
Optimal dilutions for each application to be determined by the researcher.