Further Information
Actin, alpha skeletal muscle, Alpha-actin-1, ACTA1, ACTA
For IHC-P starting dilution is: 1:25
For WB starting dilution is: 1:1000
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
- Kim, E.Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F594-F604 (2010)Haigh, S.E., et al. Neuromuscul. Disord. 20(6):363-374(2010) Yu, G., et al.Clin Neurosci 17(6):766-769(2010) Yu, C.H., et al. PLoS ONE(7), E11878 (2010)Licastro, F., et al. Curr. Pharm. Des. 16(7):783-788(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: C. Elegans, Drosophila, Xenopus, Chicken, Bovine, Mouse, Rabbit, Zebrafish, Hamster, Monkey, Pig, Yeast
This ACTA1/Alpha-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the C-terminal region of human ACTA1/Alpha-actin.
58
Actin, alpha skeletal muscle
ACTA1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
P68133
61218043
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Signal Transduction
P68133
Optimal dilutions for each application to be determined by the researcher.