Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Glycogen synthase kinase-3 beta, GSK-3 beta, Serine/threonine-protein kinase GSK3B, Gsk3b
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).
- Liu, Y., et al. Diabetologia 53(12):2600-2610(2010)
- Graham, J.A., et al. J. Biol. Chem. 285(43):32852-32859(2010)
- Ahmad, I., et al. Oncogene (2010) In press :
- Asada, N., et al. J. Neurosci. 30(26):8852-8865(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Human, Rat
This Mouse Gsk3b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of mouse Gsk3b.
56637
Glycogen synthase kinase-3 beta
Gsk3b
Mus musculus
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Q9WV60
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Cell Cycle,Neuroscience,Signal Transduction
Q9WV60
Optimal dilutions for each application to be determined by the researcher.