NSJ Bioreagents

Fascin Antibody

Product Code:
 
NSJ-R32251
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution the Fascin antibody can be stored for up to one month at 40. For long-term aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of 1) human SH-SY5Y, 2) human HeLa, 3) human K562, 4) human A549, 5) human HepG2, 6) human PC-3, 7) rat brain, 8) mouse brain and 9) mouse NIH 3T3 cell lysate with Fascin antibody. Predicted molecular weight ~55 kDa.
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Western blot testing of 1) human SH-SY5Y, 2) human HeLa, 3) human K562, 4) human A549, 5) human HepG2, 6) human PC-3, 7) rat brain, 8) mouse brain and 9) mouse NIH 3T3 cell lysate with Fascin antibody. Predicted molecular weight ~55 kDa.

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NSJ-R32251-100ug100 ug£535.00
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Further Information

Application Details:
Western blot: 0.5-1ug/ml
Application Note:
Optimal dilution of the Fascin antibody should be determined by the researcher.
Description:
Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. [UniProt]

Abnormal fascin expression or function has been implicated in breast cancer, colon cancer, esophageal squamous cell carcinoma, gallbladder cancer and prostate cancer.

Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids KKQIWTLEQPPDEAGSAAVCLRSHLGRYLAAD of human Fascin were used as the immunogen for the Fascin antibody.
Limitation:
This Fascin antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Rat
Uniprot #:
Q16658