NSJ Bioreagents

Hepsin Antibody

Product Code:
 
NSJ-R31144
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the Hepsin antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of Hepsin antibody and Lane 1: 293T; 2: NRK; 3: HeLa; 4: PANC; 5: MFC-7 cell lysate. Expected/observed size ~45KD
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Western blot testing of Hepsin antibody and Lane 1: 293T; 2: NRK; 3: HeLa; 4: PANC; 5: MFC-7 cell lysate. Expected/observed size ~45KD

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CodeSizePrice
NSJ-R31144-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Hepsin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Hepsin, also known as TMPRSS1, is an enzyme that in humans is encoded by the HPN gene. Tsuji et al.(1991) mapped the gene to 19q11-q13.2. Using cDNA microarrays, Dhanasekaran et al.(2001) examined gene expression profiles of more than 50 normal and neoplastic prostate specimens and 3 common prostate cancer cell lines. Signature expression profiles of normal adjacent prostate, benign prostatic hypertrophy, localized prostate cancer, and metastatic, hormone-refractory prostate cancer were determined. In 3 different human cell lines, Guipponi et al.(2008) found that Hepsin was stably anchored in the endoplasmic reticulum.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human Hepsin (KVSDFREWIFQAIKTHSEA) was used as the immunogen for this Hepsin antibody.
Limitation:
This Hepsin antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Rat
Uniprot #:
P05981