NSJ Bioreagents

IL-17F Antibody

Product Code:
 
NSJ-R32918
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the IL17F antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of mouse 1) spleen, 2) thymus, 3) NIH3T3 and 4) SP20 lysate with IL17F antibody at 0.5ug/ml. Predicted molecular weight: ~15 kDa (unmodified monomer), 15-20 kDa (glycosylated monomer), ~30 kDa (homodimer) and 30~40 kDa (glycosylated homodimer).

Western blot testing of mouse 1) spleen, 2) thymus, 3) NIH3T3 and 4) SP20 lysate with IL17F antibody at 0.5ug/ml. Predicted molecular weight: ~15 kDa (unmodified monomer), 15-20 kDa (glycosylated monomer), ~30 kDa (homodimer) and 30~40 kDa (glycosylated homodimer).

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NSJ-R32918-100ug100 ug£535.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western Blot: 0.5-1ug/ml,ELISA (Capture; recombinant mouse protein): 0.1-0.5ug/ml (BSA-free format available)
Application Note:
Optimal dilution of the IL17F antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Description:
Interleukin 17F, also called IL17F is involved in the regulation of normal versus aberrant T-cell responses. This gene is mapped to 6p12.2. The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. It is suggested that targeting IL17 and IL17F or antagonizing IL17R might mitigate neutrophil-mediated inflammation in CF.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A recombinant mouse protein corresponding to amino acids R29-A161 was used as the immunogen for the IL17F antibody.
Limitation:
This IL17F antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse, Rat
Uniprot #:
Q7TNI7