NSJ Bioreagents

LOXL1 Antibody

Product Code:
 
NSJ-R32201
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the LOXL1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
1 / 2
Western blot testing of human 1) A549 and 2) HeLa lysate with LOXL1 antibody. Expected/observed molecular weight ~63 kDa.~
2 / 2
IHC testing of FFPE human prostate cancer tissue with LOXL1 antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate
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Western blot testing of human 1) A549 and 2) HeLa lysate with LOXL1 antibody. Expected/observed molecular weight ~63 kDa.~
IHC testing of FFPE human prostate cancer tissue with LOXL1 antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate

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NSJ-R32201-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.1-0.5ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
Optimal dilution of the LOXL1 antibody should be determined by the researcher.
Description:
Lysyl oxidase homolog 1 is an enzyme which in humans is encoded by the LOXL1 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids AEEKCLASTAYAPEATDYDVRVLLRFPQR of human Lysyl oxidase homolog 1 were used as the immunogen for the LOXL1 antibody.
Limitation:
This LOXL1 antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q08397