NSJ Bioreagents

MERTK Antibody

Product Code:
 
NSJ-R31400
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the MERTK antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of human HepG2 cells with MERTK antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= MERTK antibody.~
2 / 2
Western blot testing of 1) human HepG2, 2) human Jurkat, 3) human K562, 4
❮❯

Flow cytometry testing of human HepG2 cells with MERTK antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= MERTK antibody.~
Western blot testing of 1) human HepG2, 2) human Jurkat, 3) human K562, 4

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CodeSizePrice
NSJ-R31400-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the MERTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Proto-oncogene tyrosine-protein kinase MER is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type(immunoglobulin-like) domains, and one tyrosine kinase domain. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. It is also very important in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human MERTK (KDGKELLGAHHAITQFY) was used as the immunogen for this MERTK antibody.
Limitation:
This MERTK antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Uniprot #:
Q12866