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Type	Category	Supplier

Cas9 Expressing Primary Cells & GPCR Expressing Cell Lines Neuromics is proud to introduce their newest pioneering research tools - human Cas9 expressing primary cells and GPCR expressing cell lines. With these modifications, the cells are valuable and versatile options for drug discovery, studying disease mechanisms, and countless other applications.
Documents	Primary Cells	Neuromics	View
VHH nanoBiTE™ Service Abnovas VHH nanoBiTE™ service focuses on developing bispecific VHH antibodies without an Fc domain, ideal for immune and tumor cell redirecting, multiple epitope targeting, and novel immuno-oncology research. Their smaller molecular size enhances tissue penetration, making them suitable for hard-to-access areas like the tumor microenvironment. The absence of an Fc region prevents unwanted immune activation by avoiding Fc receptor binding, supporting precise mechanistic action. Engineered through the genetic fusion of two VHH domains via a flexible peptide linker, VHH nanoBiTE™ ensures robust antigen binding with reduced production complexity.
Documents	Service	Abnova Corporation	View
Leadgene Indoxyl Sulfate (IS) ELISA Kit Instructions for Use Leadgene Indoxyl Sulfate (IS) ELISA Kit is a competitive enzyme-linked immunosorbent assay (competitive ELISA) for quantitative detecting total indoxyl sulfate (IS) levels in human serum samples. It is used as an aid in the diagnosis of renal function. However, it is intended for in vitro diagnostic use only, NOT suitable for use in therapeutic procedures.
Documents	Datasheets	LeadGene Biomedical	View
Gene Editing Enzymes GMP-Grade & Research-Grade Enzymes for Gene Editing
Documents	Proteins	KactusBio Inc.	View
GMP-Grade mRNA Production Enzymes KactusBio provides a range of GMP-grade enzymes suitable for mRNA production.
Documents	Proteins	KactusBio Inc.	View
Recombinant Protein Catalogue KACTUS excels in crafting and producing an array of superior-grade, highly active recombinant proteins and enzymes, catering to diverse sectors like antibody drug discovery, immunotherapy, gene therapy, and mRNA therapeutics. Our expansive catalog, boasting over 3000 recombinant proteins, encompasses a wide spectrum of targets, species, tags, and labels, each thoughtfully chosen to address the specific, unmet needs of scientists engaged in drug development. The hallmark of our product selection process is a rigorous emphasis on exceptional quality and a steadfast commitment to ensuring reliable supply, thereby upholding the highest standards of excellence and client satisfaction.
Documents	Catalogue	KactusBio Inc.	View
Versatile T7 RNA polymerases that generate less immunostimulatory mRNA Poster In vitro transcription (IVT) utilizing T7 RNA polymerase (T7 RNAP) for the synthesis of messenger RNA (mRNA) is efficient and well-established for the production of large quantities of synthetic RNA. However, T7 RNAP can generate undesirable, immunostimulatory mRNA byproducts such as double-stranded RNA (dsRNA). To reduce these concerns, we rationally engineered a series of T7 RNAP mutants and compared their functional properties to those of wild-type and commercially available T7 RNAP. Among these characteristics are dsRNA, circular RNA, processivity, and yield.
Documents	RNA	KactusBio Inc.	View
Transforming Tumor Research: Engineering MHCs as Versatile Reagents Poster When dealing with solid tumors lacking specific biomarkers, the effectiveness of adoptive T cell therapy using TCR-T treatments is limited. We believe that the absence of dependable, multifaceted MHC reagents has been a hindrance in the research and development of treatments for solid tumors. To address this unmet need, we have engineered MHC molecules in several formats with diverse applications and high stability. These improved, highly active MHC molecules have the potential to facilitate solid tumor research and development.
Documents	Cancer	KactusBio Inc.	View
GPCR VLPs & Nanodiscs for Drug Discovery Poster G protein-coupled receptors (GPCRs), also known as seven-transmembrane receptors, represent the most important class of drug targets. However, extraction and purification of membrane proteins like GPCRs, ion channels, and transporters are generally challenging due to low expression levels and the hydrophobic nature of transmembrane segments. To tackle this challenge, we have engineered and produced GPCRs in VLP and/or nanodisc formats, which have been successfully applied to GPCR antibody drug discovery and various in vitro assays.
Documents	Drug Discovery	KactusBio Inc.	View
Case Study - TCR Staining using PE-Labeled prMHC Tetramer A leading TCR company conducted an experiment using two TCR-expressing cell lines: (1) incomplete TCR expression and (2) complete TCR expression. The cell lines were stained using KACTUS PE-Labeled Human Peptide Ready HLA-A*02:01&B2M Tetramer, loaded with a peptide, cognate or not (sequence proprietary) to identify antigen-specific CD3+ cells. To load the prMHC, the peptide was mixed with the prMHC-PE tetramer at a 10:1 molar ratio. For staining, 1μg of prMHC-PE was used per 1e5 and 2e6 cells.
Documents	Tetramers	KactusBio Inc.	View
Custom SPR Services KACTUS offers experienced SPR technology services, expertly customized for various experimental protocols that meet the unique needs of your drug discovery and development.
Documents	Service	KactusBio Inc.	View
B-Xpander™ Brochure Unleash the Power of B Cell Expansion for Clinical Research & Immunotherapies
Documents	Cell Biology	AdipoGen Life Sciences	View
B-Xpander™ Flyer Unleash the Power of B Cell Expansion for Clinical Research & Immunotherapies
Documents	Cell Biology	AdipoGen Life Sciences	View
GLP-1R, GIPR & GCGR Agonists Peptide-based Tools for Obesity & Diabetes Research
Documents	Metabolism	AdipoGen Life Sciences	View
Cell Therapies – Cell Expansion Adipogen Life Sciences provides products for B & T Cell Expansion - B-Xpander and InVivoKines.
Documents	Cell & Gene Therapy	AdipoGen Life Sciences	View
Soluble Carrier Proteins Kactus dedicated team has explored a comprehensive list of full-length SLC family transporters, available as custom expression proteins.
Documents	Proteins	KactusBio Inc.	View
MHC & TCR Solutions Catalog & Custom Services for MHC Monomers, Tetramers, & Soluble TCRs
Documents	Tetramers	KactusBio Inc.	View
Laminin 521 KACTUS has successfully developed a high-quality recombinant Laminin 521 that can be applied to scientific research (research-grade) and preclinical development (preclinical-grade).
Documents	Recombinant Proteins	KactusBio Inc.	View
Cytokines Cell culture is the cornerstone for advancements in cell therapy and organoid development. KACTUS has crafted an array of premium cytokines tailored for the cultivation of cells and organoids, creating a reliable foundation for research in these areas.
Documents	Cytokines	KactusBio Inc.	View
KactusBio Company Overview Expertly Designing & Manufacturing Recombinant Proteins & Enzymes
Documents	Supplier Introduction	KactusBio Inc.	View
Full-Length Human Claudin 18.2 Claudin 18.2, a small transmembrane protein with 4 transmembrane domains and two extracellular loops, is overexpressed in a significant proportion of gastric cancers and oesophagal adenocarcinomas. In 2018, KACTUS was the first company globally to express full-length wild-type Claudin 18.2.
Documents	Proteins	KactusBio Inc.	View
AccuBaseTM Cytosine Base Editor AccuBase™ is a cytosine base editor engineered by Base Therapeutics and manufactured for global sales by KACTUS. It creatively embeds a deaminase inside the Cas protein to prevent random binding of deaminase to non-target sites, significantly reducing off-target occurrence while still maintaining high editing efficiency.
Documents	Proteins	KactusBio Inc.	View
AAV Titration ELISA Kits Detect full and empty AAV capsids specific to AAV2, AAV5, AAV6, AAV8, or AAV9 serotypes via ELISA.
Documents	ELISA	KactusBio Inc.	View
VLP & Nanodisc Displayed Antigens KactusBios has successfully developed a series of full-length multi-pass transmembrane proteins displayed on VLPs.
Documents	Proteins	KactusBio Inc.	View
DNA Amplification & Modification Enzymes Kactus provides enzymes for DNA amplification and modification
Documents		KactusBio Inc.	View

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