As part of the new CML Green Initiative (What’s that I hear you ask? Read more here!), the CML Green Initiative Committee have been holding “Eco Exchanges”. These sessions, held by our very own Cara Hetherington, are all about simple
Fresh and Frozen LeukoPaks
Apheresis was first described over 100 years ago and has been used as a therapy for a number of different diseases, including sickle cell anemia and certain types of cancer. The use of apheresis as a method for isolating enriched
Adipose Cell System
Adipocytes play an important role in energy and metabolism. Adipocyte differentiation is a developmental process that is critical for metabolic homeostasis and nutrient signaling. It is controlled by complex actions involving gene expression and signal transduction. The proliferation and differentiation
Plasma, Cord Blood and CD34+
Caltag Medsystems specialises in procuring haematopoietic cells and plasma collected from healthy and diseased donors. Our suppliers are able to isolate and purify a wide selection of human primary cells from a variety of tissues including: Cord Blood, Whole Blood,
Diseased Blood Products
Through our network of trusted suppliers Caltag Medsystems are able to offer human diseased peripheral blood, plasma, serum, and peripheral blood mononuclear cells (PBMCs). Using suppliers strategically located collection centers we are able to ensure access to donors and the
Primary cells: Human Gastrointestinal Cells
The gastrointestinal (GI) system includes a number of highly specialised cell types each differentiated to perform a specific function. The most common are epithelial cells, which are diversely specialised to carry out most of the functions which are specific to
Epitope Tag Antibodies and Kits
High Sensitivity and Specificity Excellent Purification Useful for IP, IHC, WB, FCM and other applications Over 25 different tags available MBLI offers a comprehensive line of high-quality antibodies and kits for your epitope tag experiments. These products are highly cited
What’s the KD of my Antibody?
Understanding binding affinity is an important part of the drug discovery process, ensuring that therapeutic antibodies that bind their targets selectively and specifically. It also helps to understand the intermolecular interactions driving biological processes, structural biology, and structure-function relationships. KD
Protective role for IL-36 cytokines in obesity and metabolic disease
Interleukin-36α, β and γ (IL-36α, β and γ), members of the interleukin-1 (IL-1) family, are pro-inflammatory cytokines mainly involved in skin inflammatory diseases, but also in the inflammation of lung or gut. Recently, the lab of Prof. Patrick T. Walsh
Stress granules inhibit NLRP3 inflammasome activation by sequestering the helicase DDX3X
Inflammasomes are large multimolecular complexes involved in innate immune response and driving cell fate towards cell death, called pyroptosis. Stress granules are aggregates formed during cellular stress with pro-survival role composed of proteins and mRNA molecules. Recently, the lab of