TransFix® is designed for stabilisation of peripheral blood and cerebrospinal fluid to enumerate lymphocyte subpopulations by flow cytometry. However, researchers have developed many new and innovative uses of TransFix. We’ve presented a selection of publications to highlight the versatility of
Blood Stabilisation: The Importance in a Clinical Setting
Without stabilisation, flow cytometric analysis of blood samples must be performed within 48 hours of venepuncture, as apoptosis and proteolytic degradation of cellular markers will detrimentally affect the immunophenotypic profile. Blood samples older than 48 hours are often no longer
Validating the use of TransFix to stabilise cerebrospinal fluid (CSF) for flow cytometry immunophenotyping of haematological malignancies
Cytomark, a division of Caltag Medsystems, recently presented a scientific poster at the ICCS2017 conference in collaboration with Bristol Royal Infirmary (Bristol, UK) “Validating the use of TransFix to stabilise cerebrospinal fluid (CSF) for flow cytometry immunophenotyping of haematological malignancies”
Inter-laboratory Comparison of the TransFix/EDTA Vacuum Blood Collection Tube (TVT) with the 5 mL Cyto-Chex® BCT
Cytomark, a division of Caltag Medsystems, recently presented a scientific poster at the ICCS2017 conference in collaboration with the Royal Hallamshire Hospital (Sheffield, UK), Royal Sussex County Hospital (Brighton, UK), and Roswell Park Cancer Institute (Buffalo, NY, USA). “Inter-laboratory Comparison of the TransFix/EDTA
Reduce Variability in Clinical Trials by Stabilizing Samples
TransFix/EDTA Vacuum Blood Collection Tubes (TVTs) have been cleared for IVD use in the United States and Europe. Prefilled with TransFix and K3EDTA, these tubes allow for convenient collection, anticoagulation, and instant stabilization of peripheral blood for flow cytometric analysis.
Blood Controls for Flow Cytometry
Routine haematological testing requires the use of reference material during machine set up such that validation prior to analysis of patient samples can be performed. Many also require repeat use of reference controls throughout the running period of the machine,
Cell Fixation and Permeabilistation Kit for Intracellular Staining
Intracellular staining of protein biomarkers using antibodies in flow cytometry has opened up a diversity of new options for phenotypic and functional characterisation of cells in both research and clinical diagnosis. Definitive phenotypic identification of certain cell types can require labelling