The process of T cell exhaustion & how it can be harnessed for immuno-oncology drug discovery and for immune checkpoint screening of drug candidates.
Therapeutic antibodies dominate pipelines and top selling drugs at major pharmaceutical companies. They have proven to be valuable tools in the fight against diseases from cancer and autoimmune disorders to infectious and neurodegenerative diseases. Beyond therapeutics, monoclonal antibodies shown to
AdipoGen’s SARS-CoV-2 Spike Protein (D614G) (Stable Trimer) (rec.) (His) is a full-length soluble SARS-CoV-2 Spike protein.
Immunotherapies such as monoclonal antibodies, bispecific antibodies (Bi-specific T-cell engagers or BiTEs) and adoptive T-cell therapies (e.g. CAR-modified T-cell) have provided great advances in cancer treatment. However, testing new therapies is not without risk. The most common and potentially severe
Understanding binding affinity is an important part of the drug discovery process, ensuring that therapeutic antibodies that bind their targets selectively and specifically. It also helps to understand the intermolecular interactions driving biological processes, structural biology, and structure-function relationships. KD
BeCytes Biotechnologies offers a range of animal hepatocytes for research purposes.
What is mitophagy? It is when damaged mitochondria are removed from the cell by autophagy. The damaged mitochondria end up in lysosomes for their final disposal. This whole process is to maintain and assure proper cellular function. The importance of
Visualizing protein-protein interaction (PPI) is pretty neat. You are able to glimpse into a really unique aspect of nature that many people don’t get to see. It’s like watching lions and zebras interact but without the bloody violence. However, anyone