ScienCell’s Human Hepatic Stellate Cells (Product Code: SC-5300) cultured in Stellate Cell Medium (Product Code: SC-5301) is an optimal model for many research areas including liver injury, hepatic development, regeneration, xenobiotic responses, intermediary metabolism, and immunoregulation.
Studying HHSteC will lead to therapies for hepatic fibrosis and may help to reduce morbidity and mortality in patients with chronic liver injury.
- Isolated from human liver
- Each vial contains >5 x 105 cells in 1 ml volume
- Guaranteed to further expand for 15 population doublings
- Recommended medium: Stellate Cell Medium (Product Code: SC-5301)
Caltag Medsystems is the distributor of ScienCell products in the UK and Ireland. If you have any questions about these products, please contact us.
Featured Publications:
Che J, Chan ES, Cronstein BN. (2007) “Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway.” Mol Pharmacol. 72: 1626-36.
Martín-Vílchez S, Sanz-Cameno P, Rodríguez-Muñoz Y, Majano PL, Molina-Jiménez F, López-Cabrera M, Moreno-Otero R, Lara-Pezzi E. (2008) “The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells.” Hepatology. 47: 1872-83.
Semela D, Das A, Langer D, Kang N, Leof E, Shah V. (2008) “Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function.” Gastroenterology. 135: 671-9.