Innovative Modes of Culture
BioArtificial Livers (BALs)
HepaRG™ cells can be cultured in 3D bioreactors to generate an in-vivo-like assembly of highly polarised cells with high and sustained CYP activities. This makes them a promising cell type for use as liver assist devices or BALs.
Transgenic liver humanized animals with HepaRG™ cells
HepaRG™ cells can be transplanted into chimeric mice to repopulate their livers and express human primary hepatocyte–specific genes and proteins. Such a HepaRG™-mouse combination represents a promising model for in-vivo studies of drug metabolism and hepatitis virus infections.
Spheroids
Micropatterns
Dynamic fluidic models
Co-culture models
Stem cell cultures
Please click here to view the HepaRG products.
Innovative Modes of Culture