Therapeutic antibodies dominate pipelines and top selling drugs at major pharmaceutical companies. They have proven to be valuable tools in the fight against diseases from cancer and autoimmune disorders to infectious and neurodegenerative diseases. Beyond therapeutics, monoclonal antibodies shown to
Programmed cell death is a selective process of physiological cell deletion. It plays a major role in developmental biology and in maintenance of homeostasis in vertebrates. For example, during maturation, T cells recognising self antigens are destroyed by programmed cell
With more than 800 Research Grade Biosimilar antibodies in ProSci’s catalogue, these unique tools are available for researchers worldwide. Explore the world of biosimilars! In 1986, the first monoclonal antibody became licensed–an event occurring nine years after the generation of
Whenever our immune system is faced with a challenge, be it a multicellular parasite, a bacteria, a virus, or even cancer, this threat is detected and sampled primarily by the protein sequence of the pathogen in question. Other aspects of
Peripheral blood mononuclear cells (PBMCs) are a diverse mixture of highly specialized immune cells that play key roles in keeping our bodies healthy. This brief review tells a short story about PBMCs starting with their origin, the different immune cells
Immunotherapies such as monoclonal antibodies, bispecific antibodies (Bi-specific T-cell engagers or BiTEs) and adoptive T-cell therapies (e.g. CAR-modified T-cell) have provided great advances in cancer treatment. However, testing new therapies is not without risk. The most common and potentially severe
Apheresis was first described over 100 years ago and has been used as a therapy for a number of different diseases, including sickle cell anemia and certain types of cancer. The use of apheresis as a method for isolating enriched
Adipocytes play an important role in energy and metabolism. Adipocyte differentiation is a developmental process that is critical for metabolic homeostasis and nutrient signaling. It is controlled by complex actions involving gene expression and signal transduction. The proliferation and differentiation
Caltag Medsystems specialises in procuring haematopoietic cells and plasma collected from healthy and diseased donors. Our suppliers are able to isolate and purify a wide selection of human primary cells from a variety of tissues including: Cord Blood, Whole Blood,
Through our network of trusted suppliers Caltag Medsystems are able to offer human diseased peripheral blood, plasma, serum, and peripheral blood mononuclear cells (PBMCs). Using suppliers strategically located collection centers we are able to ensure access to donors and the