COVID-19 infected cells can be recognized by T-cells only after SARS-CoV-2 peptides are processed and presented in the context of self MHCs. Identifying these peptides have essential utilities: Immune monitoring: Using peptide-MHC tetramers to assess vaccine-induced immunity Designing potent vaccines
Interleukin-6 release in response to Coronavirus 19
Coronavirus 19 is known to infect the respiratory tract and cause mild or highly acute respiratory syndrome. A consequence of this is the release of pro-inflammatory cytokines, including interleukin (IL)-1β and IL-6 (1). This hyperinflammatory response is thought to be
Fresh or Frozen Primary Cells: Helpful tips for choosing the right format for your research.
Fresh or Frozen Primary Cells: Which one should I choose? Deciding to purchase fresh or frozen primary cells may not be as simple as you think. There are many factors that may influence your decision, such as cell type, cell
StemExpress NEW Frozen Leukopak
Basic biomedical research into many human diseases and disorders often starts with living, functional cells and allows extraordinary scientific and technological advances in medical science. Yet, potential delays in accessing these cells can hinder forward progress of research and postpone
Peripheral Blood Mononuclear Cells: A Brief Review
Peripheral blood mononuclear cells (PBMCs) are a diverse mixture of highly specialized immune cells that play key roles in keeping our bodies healthy. This brief review tells a short story about PBMCs starting with their origin, the different immune cells
Coronavirus (COVID-19) Research Tools
Recently, scientists have discovered a novel strain of Coronavirus (COVID-19) that is more deadly than SARS-CoV and MERS-CoV combined. This has caused a massive viral outbreak globally, and due to the lack of information about this strain, there are limited
The Dark Side of CAR-T Therapy – Cytokine Release Syndrome (Diaclone)
Immunotherapies such as monoclonal antibodies, bispecific antibodies (Bi-specific T-cell engagers or BiTEs) and adoptive T-cell therapies (e.g. CAR-modified T-cell) have provided great advances in cancer treatment. However, testing new therapies is not without risk. The most common and potentially severe
What’s New at Diaclone?
The Diaclone name has stood for quality and reliability for 34 years. Based in Besançon, France, Diaclone pride themselves on excellence in monoclonal antibody and immunoassay development and manufacture. The expanding range of Diaclone immunology products is specifically designed to
Clinically relevant Mesenchymal Stem Cells
Rapid advancements in mesenchymal stem cells (MSCs) research are shedding light on disease processes of musculoskeletal tissue, tissue regeneration, immune modulation and epigenetics. To further the understanding of MSCs disease mechanisms and therapeutic approaches, we offer Renovos research-grade mesenchymal stem
Healthy & Diseased Mesenchymal Stem Cells and Plates
Caltag Medsystems is now offering MSCs from donors of clinically relevant age range. Mesenchymal stem cells (MSCs) from osteoarthritic donors have been used extensively as research tools and can be used for Regenerative Medicine, Musculoskeletal Diseases, Immuno Modulation and Epigenetics. To aid the research of