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CD1d

CD1d molecules are non-polymorphic MHC class I-like proteins. These are a type of non-classical MHCs. They present phospholipid and glycosphingolipid antigens to invariant Natural Killer T (iNKT) cells, a subset of CD1d-restricted T cells. This axis is involved in the

MHC Class II Tetramers

T cell receptors (TCRs) expressed on the surface of T cells specifically recognise and bind to complexes of major histocompatibility complex (MHC) molecules and peptide fragments. CD4+ T cells, which include helper and regulatory T cells, recognise complexes of MHC class

MHC Class I Tetramers

T cell receptors (TCRs) expressed on the surface of T cells specifically recognise and bind to complexes of major histocompatibility complex (MHC) molecules and peptide fragments expressed on the surface of antigen-presenting cells. CD8+ T cells, also called cytotoxic T

Exploring Single Domain Antibodies for Tauopathy Treatment

Researchers at New York University Grossman School of Medicine, led by Erin E. Congdon, have explored the potential of single-domain antibodies (sdAbs) in treating tauopathies, including Alzheimer’s disease. The results of their study were recently published in The Lancet® and focused