AdipoGen Life Sciences have a range of reagents for Gasdermin research
Inflammasomes and Gasdermin D Signaling Pathways
Autoimmune Disease Biomarkers APRIL & BAFF
The B cell-stimulating molecules, BAFF (B cell activating factor, also known as BLyS; TALL-1; CD257 or TNFSF13B) and APRIL (a proliferation-inducing ligand, also known as CD256 or TNFSF13), are critical factors in the maintenance of the B cell pool and
Antibody Validation
A committee, including Adipogen, made guidelines for antibody validation & detailed context-dependent measures to be followed by antibody suppliers.
3Helix Overview and Applications
Collagen is the most abundant protein in the human body. It is a critical component of almost all organs and tissues, providing the framework for cell attachment and growth. Collagen degradation regulates normal tissue remodelling which occurs during development, homeostasis
Revel the Mechanisms of Host Defense by Cross-regulation of Toll-like Receptor (TLR) Responses
A recent Nature Immunology paper describes the epigenetic landscape that results from the integration of the inflammatory cytokines type I interferons and TNF. This comprehensive epigenomics approach to the analysis of human macrophages showed that the proinflammatory cytokines TNF and type
Do You Really Know About Peptides?
Peptides are the organic molecule made up 2 to 40 amino acids, structurally same as protein but smaller. The bonds present in peptides are termed as a peptide bond (1). The bonds are formed between amino group (-NH2) of one amino acids and the
A Comprehensive Interpretation of Proteins
DEFINITION Proteins are the high molecular weight material which on complete hydrolysis gives amino acids. The word protein is derived from Greek word Proteiosmeans primary or holding first place or pre-eminent [1]. BIOMEDICAL IMPORTANCE OF PROTEIN They are: 1). Proteins are the main
Risk Factors and Treatment of Depression
Depression, in psychology, is a mood or emotional state marked by feelings of low self-worth or guilt and a reduced ability to enjoy life. A person who is depressed usually experiences several of the following symptoms: feelings of sadness, hopelessness, or
Tips for Staining Rare Antigens with MHC Tetramers
When performing staining with MHC tetramers, there may be certain cases where the staining is unclear. An example could be in certain cases where an antigen-specific T cell population of interest has a low frequency. The following tips discussed in
Skin: Fresh & Frozen Samples, Isolated Cells and Subcellular Fractions
Caltag Medsystems supply both fresh and frozen human skin for use in different applications including: drug permeation, skin irritation, toxicology, and metabolism, as well as primary cell isolation. In addition, we provide a wide range of skin cells: fibroblasts, keratinocytes,