CnT-Prime is a fully defined medium, that is free of all human and animal-derived components. It uses an optimised basal medium with additional trace elements, protective antioxidants and vitamins. This basal medium is then supplemented with a range of Progenitor
Detection of human DJ-1/PARK7
The CircuLex Human DJ-1/PARK7 ELISA Kit has been developed to measure the concentration of human DJ-1/PARK7 from human serum, plasma, cell lines and conditioned media. DJ-1 (PARK7/CAP1/RS) is expressed in many cells and tissues, including the brain. Over-expression of DJ-1
Flagellin – A TLR5/NLRC4 Agonist
Toll-like receptor 5 (TLR5) recognises flagellin from both Gram-positive and Gram-negative bacteria. Activation of the receptor stimulates the production of proinflammatory cytokines, such as TNF-α, through signalling via the adapter proteins MyD88, TIRAP and TRIF. Flagellin is the subunit protein
Pam3CSK4 – a TLR1/2 Agonist
Toll-like receptor 1 (TLR1) recognises pathogen-associated molecular patterns (PAMPS) with a specificity for Gram-positive bacteria. TLR1 recognises peptidoglycan and triacyl lipoproteins in concert with TLR2. Pam3CSK4 is a selective agonist to the TLR1/TLR2 heterodimer complex. It is a cell permeable
CaM Kinase II Assay
CycLex® CaM kinase II Assay Kit measures activity of CaM kinase II in cell lines/tissue homogenates & screens for CaM Kinase inhibitors/activators.
Caesin Kinase-2 Assay / Inhibitor Screening Kit
The CycLex® CK2 Assay / Inhibitor Screening Kit is designed to measure the activity of purified Casein Kinase-2 (CK2) for the rapid and sensitive evaluation of CK2 inhibitors or activators. The phospho-specific monoclonal antibody used in this CK2 assay kit
IDH Antibodies
MBL offers highly-specific IDH antibodies to mutant forms of IDH1 & IDH2 which can be used to detect mutated IDHs in specimens of low tumour occupancy.