Irisin is a protein cleaved from fibronectin type III domain-containing protein 5 (FNDC5) and has a beneficial role in adipose tissues, bone and brain. A recent study published in Nature Medicine by the labs of O. Arancio, S.Ferreira & F.G.
Manganese (Mn2+) as a New Activator of the NLRP3 Inflammasome in the Brain
Inflammasomes are implicated in physiological and pathological inflammation including neurodegenerative disorders such Parkinson or Alzheimer diseases. Divalent manganese (Mn2+) activates chronic inflammation leading to increase of neurotoxicity. Recently, the lab of A.G. Kanthasamy (Iowa State University, US) showed that Mn2+ activates
Erythroferrone (human) ELISA Kit – The only Specific & Sensitive Assay on the Market!
Sandwich ELISA Kit based on two antibodies for the in vitro quantitative determination of human Erythroferrone in supernatants, serum and plasma.
BioActs – Flamma Fluor Dyes
The Flamma® Fluor series is a panel of proprietary fluorescent dyes with brighter fluorescence performance than conventional dyes and with a broad coverage of the whole spectra from UV to NIR. It is applicable with most fluorescence equipment and for
BioActs – Fluorescent FSD Fluor Dyes
The FSD™ Fluor series is a new panel of proprietary fluorescent dyes with excellent fluorescence intensity and high quantum yield compared to conventional fluorescent dyes. The fluorescence intensity is also excellent after binding with bio-molecule targets (antibodies, peptides, proteins, etc.).
Recombinant Monoclonal Antibodies [RecMAbs™] – Produced with No Use of Animals
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Antibody phage display is an in vitro technology to generate recombinant monoclonal antibodies (RecMAbs™) without the use of animals.
Inflammasomes − Caspase-1 Activation Scaffolds
An inflammasome represents a high molecular weight complex that activates inflammatory caspases and activates cytokines of the IL-1 family.
T Cell Immune Checkpoints for Immuno-Oncology Research
AdipoGen Life Sciences offers a broad panel of immune checkpoint reagents, including recombinant proteins, antibodies and ELISA Kits.
Inflammasomes and Gasdermin D Signaling Pathways
AdipoGen Life Sciences have a range of reagents for Gasdermin research
Autoimmune Disease Biomarkers APRIL & BAFF
The B cell-stimulating molecules, BAFF (B cell activating factor, also known as BLyS; TALL-1; CD257 or TNFSF13B) and APRIL (a proliferation-inducing ligand, also known as CD256 or TNFSF13), are critical factors in the maintenance of the B cell pool and