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Nanobody (VHH) Development Service
Bacterial vs. Mammalian Expression Systems
Expressing recombinant antibodies can be done in all kinds of systems. Many different cell lines can be used for expressing antibodies, including mammalian cells like HEK293 or CHO, or even yeast, plant or insect cell lines. Each expression system has
Antibody Basics: Rabbit Monoclonal Antibodies
This ProSci blog covers the the major rabbit monoclonal antibody development techniques most commonly used, including phage display, rabbit hybridoma, B-cell cloning, and individual plasma cell cloning. Antibody Basics: Rabbit Monoclonal AntibodiesRabbit Monoclonal Antibody Monoclonal antibodies developed in mice have
The Antibody Basics Series: Table of Contents
Not too long ago, we published The 5 A’s of Antibodies infographic, which provides a brief explanation of all what goes into the process of generating custom antibodies against specific targets. Our next step is to begin providing summaries of
ProSci’s 5 A’s of Antibody Development Infographic
Antibody development is multi-faceted process that begins with the target to which you wish to develop antibodies against: the antigen. To elicit an immune response we must select the appropriate adjuvant to be mixed with the antigen for immunization. Which
Antibody Basics: Hybridoma
Hybridoma Development Hybridoma technology is the core technique used to develop monoclonal antibodies at ProSci. A hybridoma is a single cell that consists of a cancerous myeloma cell and an immune B-cell which have been fused together into a single