The PD-1/PD-L1 or PD-L2 signalling pathway is a negative regulatory mechanism that inhibits T cell proliferation and cytokine production.
PD-1 [CD279]/PD-L1 [CD274] Pathway
![PD-1 [CD279]/PD-L1 [CD274] Pathway](https://www.caltagmedsystems.co.uk/information/wp-content/uploads/pd-1-600x400px-600x300.png "PD-1 [CD279]/PD-L1 [CD274] Pathway")
SURAMIN – A Multifunctional Small Molecule with over 100 Years of History
Suramin is a multifunctional molecule with a wide array of potential applications, from parasitic and viral diseases to cancer, snakebite and autism.
Nano Vaccines Induce T Cell Immunity and Control of Tumour Growth
Using nanoparticle technology in making vaccines for infectious diseases/cancer is advancing & enhances the immunogenicity of some vaccine candidates.
Is your drug candidate able to reverse the T Cell Exhaustion-like state in MBL’s in vitro functional screening assay?
The process of T cell exhaustion & how it can be harnessed for immuno-oncology drug discovery and for immune checkpoint screening of drug candidates.
Research Grade Biosimilar Antibodies from ProSci
Therapeutic antibodies dominate pipelines and top selling drugs at major pharmaceutical companies. They have proven to be valuable tools in the fight against diseases from cancer and autoimmune disorders to infectious and neurodegenerative diseases. Beyond therapeutics, monoclonal antibodies shown to
The Role of Monoclonal Antibodies & Biosimilars in Research – ProSci Inc.
With more than 800 Research Grade Biosimilar antibodies in ProSci’s catalogue, these unique tools are available for researchers worldwide. Explore the world of biosimilars! In 1986, the first monoclonal antibody became licensed–an event occurring nine years after the generation of
T Cell Immune Checkpoints for Immuno-Oncology Research
AdipoGen Life Sciences offers a broad panel of immune checkpoint reagents, including recombinant proteins, antibodies and ELISA Kits.
Evaluating the biological activity of a cancer vaccine with the HLA-A*02:01 QuickSwitch™ Quant platform
Principle of the cell-based T2 shift assay and the cell-free QuickSwitch™ Quant assay Comparison of the cell-based T2 shift assay and the cell-free QuickSwitch™ Quant assay Immuno-oncology is a growing field in which different strategies such as immune modulators, vaccines
News Release Journal Article Highlights AlbuVoid™ in Cancer Functional Proteomic Analysis
Biotech Support Group reports on a new research report which highlights the simplicity and efficiency of their proteomic sample preparation technology as an initial enrichment step to the Array Bridge (St. Louis, MO) Protein Elution Plate (PEP). The combined methods
Why pure exosome isolation matters
Exosomes are cell-derived vesicles originating from multi-vesicular bodies and found in biological fluids such as blood, saliva, urine, and breast milk. Sizes of these extracellular vesicles (EVs) range between 30-100 nm. Due to their capacity to transfer proteins, lipids and