Epidermal Levels of Staphylococcus Aureus Are Affected by a Peptide Produced by Other Skin Dwelling Bacteria Staphylococcus aureus is common to many of people’s ski n microbiome, and is generally harmless; however, in high population density the bacteria can lead to atopic
Problems with Immunotherapy
Pairs of proteins that act as T-cell co-signaling receptors are called immune checkpoints. These cell surface receptors can send positive or negative signals to T cells, instigating a response from the immune system to either stimulate the immune system against
January 2017: The Antibody Update
Mitigating the Reproducibility Crisis in Cancer Drug Research Reproducibility has been highlighted as one of the main problems when validating cancer research. Scientists with the The Reproducibility Project have opted to begin pragmatically reviewing the reproducibility of the research released
T-cell Activation: The Purpose of CD28, CTLA-4, and CD80/CD86
A Guide to CD28, CTLA-4, and CD80/CD86 Interaction and Signaling Immune checkpoint receptors like CD28 and CTLA-4 have been of great interest in the research of cancer immunotherapy. These receptors and their ligands are part of what regulates T-cell activation
December 2016: The Antibody Update
Merck’s Ebola Vaccine is 100% Effective An extremely effective Ebola virus vaccine created by Merck was recently tested in Guinea with 100% effectiveness. Though the vaccine is late for the worst part of the infection, the results are so promising
November 2016: The Antibody Update
China Perform First Injection of CRISPR Modified Cells into a Person Use of CRISPR-Cas9 in human cells for treatment of disease has been a controversial topic amongst scientists since the discovery of the powerful gene editing tool. In this clinical
October 2016: The Antibody Update
The Nobel Prize in Medicine was Awarded to Yoshinori Ohsumi for His Work on Autophagy Autophagy is the cellular process that regulates a cells ability to degrade parts of itself that must be replaced. Yoshinori Ohsumi’s work in autophagy has proven to
August 2016: The Antibody Update from ProSci
ProSci’s top news picks for August 2016 include a study on T-cell activity inside tumor tissue, the potential effects of Zika virus in adults, and mRNA therapeutics. T-cells Run
June 2016: The Antibody Update from ProSci
This months ProSci Antibody Update’s news includes the first CRISPR/Cas9 cancer therapeutic’s entry into clinical trials, how mosquito saliva assists viruses in proliferation, and the latest update on antibody validation. First CRISPR/Cas9 Therapeutic Clinical Trials StartingProSci Blog Antibody UpdateCRISPR Cas9
What do mitochondria have to do with mitophagy?
What is mitophagy? It is when damaged mitochondria are removed from the cell by autophagy. The damaged mitochondria end up in lysosomes for their final disposal. This whole process is to maintain and assure proper cellular function. The importance of