Manumycin A is an inhibitor of exosome biogenesis & secretion. Targeting exosome biogenesis could exert RAS signalling inhibitors’ anticancer effects.
Why pure exosome isolation matters
Exosomes are cell-derived vesicles originating from multi-vesicular bodies and found in biological fluids such as blood, saliva, urine, and breast milk. Sizes of these extracellular vesicles (EVs) range between 30-100 nm. Due to their capacity to transfer proteins, lipids and