PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. PD-L1 can bind to PD-1, which mediates inhibitory signals from the APC. ProSci Inc. offers an extensive range
PD-1 Immune Checkpoint
The PD-1 protein is a negative co-stimulatory receptor that can bind two different but related ligands, PD-L1 and PD-L2. Upon binding, signals generated by PD-1 inhibit the activation of the immune response in the absence of “danger signals.” ProSci Inc.
A Brief Introduction to PD-1 Antibodies and Immunotherapy
President Jimmy Carter’s cancer remission was wonderful news, but as some outlets [1] noted, it is important to understand that not all patients are responding as well to similar treatments, and that there is currently still no “cure” for cancer.