T-Cell Receptors (TCRs) recognise and bind to complexes composed of Major Histocompatibility Complex (MHC) molecules and specific peptides expressed on the surface of antigen-presenting cells. T cell receptors (TCRs) expressed on the surface of T cells specifically recognise and bind
Transficient™ and siRfficient™: Superior Transfection Activity against other Commercial Reagents in Numerous Adherent Cell Types
Transficient™ and siRfficient™ from MBL International are transfection reagents that provide superior transfection efficiency for primary cells and a wide variety of cell lines, including those “hard-to-transfect” cell lines. They are a cost effective and highly efficient tool for your
The Fas and the Furious 2: The Importance of Fas in Cancer
Given the prominent role of Fas in many important cell functions (Read: 7 Facts to Catch You Up to Speed on Fas). Fas has been implicated in a variety of disease states such as cancer. Here are some major findings
The Fas and the Furious: 7 Facts to Catch You Up to Speed on Fas and How a Fas Antibody Can Help Your Research
Fas antigen is a receptor protein that has been linked to many diseases such as cancer(1) and autoimmune diseases(2). Here are seven findings from research on this protein to catch you up to speed on Fas: Fas is mainly involved
Give Your Research 100% With a S100 Antibody
S100 proteins are a family of proteins known for their role in a variety of cellular pathways and diseases. This blog post will catch you up on the latest research on these important proteins. The S100 protein family consists of
Elevate Your Research Part 3: New Pathways of Study For Your PCSK9 ELISA Kit
As discussed in two prior blog posts, PCSK9 has primarily been studied for its role in regulating cholesterol levels and as a target for treatments to lower cholesterol. However, PCSK9 has been found to be involved in many other important pathways. This
Elevate your Cholesterol Research Part 2: How Our PCSK9 ELISA Kit Can Help You
As discussed in a previous blog post, inhibiting PCSK9 from binding to the LDL receptor results in lower LDL cholesterol levels in the bloodstream. Research on PCSK9 has explored how it can be targeted in treatments for hypercholesterolemia (high cholesterol)
Elevate Your Cholesterol Research: How a PCSK9 ELISA Kit Can Help You
Ever wonder how cholesterol levels are regulated? One of the major regulators is a molecule called proprotein convertase subtilisin/kexin type 9 or PCSK9 for short! PCSK9 has been implicated in causing hypercholesterolemia (high cholesterol), and diseases such as coronary heart
Stop Crying in the Lab: How Cry Antibodies Can Help Your Research
Tiredness and frustration often mount after long nights in the lab. Why can’t our bodies adjust and allow us to maintain our energy through the night? The answer lies in our circadian rhythms. Circadian rhythms are the daily cycle
Help! My mouse tetramer stained ALL the CD8+ T cells!
You’re sitting at your flow cytometer, staring at your CD8 x tetramer plot in anticipation of a tiny but meaningful group of dots appearing in the upper right quadrant. You hold your breath, click “acquire,” and watch… Wait, what? What’s