PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. PD-L1 can bind to PD-1, which mediates inhibitory signals from the APC. ProSci Inc. offers an extensive range
Problems with Immunotherapy
Pairs of proteins that act as T-cell co-signaling receptors are called immune checkpoints. These cell surface receptors can send positive or negative signals to T cells, instigating a response from the immune system to either stimulate the immune system against