Therapeutic antibodies dominate pipelines and top selling drugs at major pharmaceutical companies. They have proven to be valuable tools in the fight against diseases from cancer and autoimmune disorders to infectious and neurodegenerative diseases. Beyond therapeutics, monoclonal antibodies shown to
When selecting an antigen to use for your project, the considerations required can be overwhelming. ProSci wants your antibody project to run smoothly so your work can be done without interruption. For them to deliver high-performance antibodies, they need the
Expressing recombinant antibodies can be done in all kinds of systems. Many different cell lines can be used for expressing antibodies, including mammalian cells like HEK293 or CHO, or even yeast, plant or insect cell lines. Each expression system has
The three most common methods to develop recombinant antibodies include display systems, direct B-cell cloning, or the use of pre-existing hybridomas.
Immunogens and Carrier Proteins What is an immunogen? An immunogen is a specific type of antigen that is able to elicit an immune response. Antibody development is dependent on a humoral immune response mediated by immune cells recognising a molecule
ProSci’s roots lie in the research of the Human Immunodeficiency Virus and working to develop a neutralising vaccine against it. Below is an “abstract of abstracts” summarising the research performed over the last several years that has built their business
Antibodies are produced in the body to serve 3 major purposes in the immune system: neutralisation, opsonisation, and complement protein activation. Each of these functions helps to protect the body from potentially harmful pathogens. Neutralisation Neutralisation occurs when the antibodies
With more than 800 Research Grade Biosimilar antibodies in ProSci’s catalogue, these unique tools are available for researchers worldwide. Explore the world of biosimilars! In 1986, the first monoclonal antibody became licensed–an event occurring nine years after the generation of
It has been two years since the outbreak of coronavirus disease 2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the cause of the pandemic and has only gotten more complex for scientists to study. Studies of
Monkeypox’s genetic code is similar to smallpox so known vaccines & anti-viral treatments are effective in reducing its spread & physiological effects.