NSJ Bioreagents

P Glycoprotein Antibody / MDR1 / ABCB1

Product Code:
 
NSJ-RQ5205
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
FDB-1
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store the MDR1 antibody at -20°C.
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Western blot testing of human HeLa cell lysate with MDR1 antibody. Expected molecular weight: 141-180 kDa depending on glycosylation level.
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Western blot testing of human HeLa cell lysate with MDR1 antibody. Expected molecular weight: 141-180 kDa depending on glycosylation level.

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NSJ-RQ5205-100ul100ul£535.00
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Further Information

Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the MDR1 antibody should be determined by the researcher.
Description:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human P Glycoprotein / ABCB1 / MDR1 was used as the immunogen for the MDR1 antibody.
Limitation:
This MDR1 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P08183