Further Information
Caspase-9 Antibody: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, MCH6, Caspase-9, Apoptotic protease Mch-6, CASP-9
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
ICC: 1:50 - 1:200
IF: 1:50 - 1:100
IP: 1:20 - 1:50
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant protein of human Caspase 9
842
caspase 9, apoptosis-related cysteine peptidase
CASP9
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 37kDa, 39kDa, 46kDa
Affinity purification
Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction
P55211
Optimal dilutions for each application to be determined by the researcher.