Further Information
isocitric dehydrogenase subunit gamma, isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, gamma subunit, isocitrate dehydrogenase [NAD] subunit gamma, OTTHUMP00000025988, OTTHUMP00000025987, OTTHUMP00000025984, NAD+-specific ICDH, NAD(+)-specific ICDH subunit gamma, NAD (H)-specific isocitrate dehydrogenase gamma subunit, IDH-gamma, H-IDHG, isocitrate dehydrogenase 3 (NAD+) gamma, IDH3G
WB: 1:500 - 1:2000
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 40-170 of human IDH3G (NP_004126.1).
3421
isocitrate dehydrogenase 3 (NAD+) gamma
IDH3G
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 43kDa
Affinity purification
Cancer, Signal Transduction
P51553
Optimal dilutions for each application to be determined by the researcher.