Further Information
NTRK1, Oncogene TRK, TrkA/NGF receptor, Tropomyosin-related kinase A, TRK, TRK1, Tyrosine kinase receptor, Tyrosine kinase receptor A, gp140trk, MTC, p140-TrkA, Trk-A, TRKA
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NTRK1 (NP_002520.2).
4914
neurotrophic tyrosine kinase, receptor, type 1
NTRK1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 110kDa
Affinity purification
Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction
P04629
Optimal dilutions for each application to be determined by the researcher.