Further Information
CYP2E1, CPE1, CYP2E, P450-J, P450C2E
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:20 - 1:100
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 234-493 of human CYP2E1 (NP_000764.1).
1571
cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2E1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 56kDa
Affinity purification
Cancer, Signal Transduction
P05181
Optimal dilutions for each application to be determined by the researcher.