Further Information
NDUFS1, PRO1304, OTTHUMP00000206345, NADH-coenzyme Q reductase, NADH dehydrogenase (ubiqui) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase), 75kDa, MGC26839, complex I, mitochondrial respirato, CI-75Kd, CI-75k
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 80-290 of human NDUFS1 (NP_004997.4).
4719
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 79kDa
Affinity purification
Apoptosis, Cancer, Cell Cycle, Neuroscience
P28331
Optimal dilutions for each application to be determined by the researcher.