Further Information
PEX5, peroxisomal biogenesis factor 5, FLJ50634, FLJ50721, FLJ51948, PTS1-BP, PTS1R, PXR1, OTTHUMP00000238192, OTTHUMP00000238193, OTTHUMP00000238194, OTTHUMP00000238195, OTTHUMP00000238353, OTTHUMP00000238354, OTTHUMP00000238356, PTS1 receptor, peroxin-5
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PEX5 (NP_000310.2).
5830
peroxisomal biogenesis factor 5?
PEX5
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 70-85kDa
Affinity purification
Signal Transduction
P50542
Optimal dilutions for each application to be determined by the researcher.