Further Information
CPN1, CYP11B, FHI, P450C11, cytochrome P450 11B1, mitochondrial, CYPXIB1, cytochrome P-450c11, cytochrome P45family 11, subfamily B, polypeptide 1, cytochrome P45subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1, cytochrome P450C11, cytochrome p450 XIB1, steroid 11-beta-hydroxylase, steroid 11-beta-monooxygenase
WB: 1:500 - 1:2000
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B1 (NP_000488.3).
1584
cytochrome P450 family 11 subfamily B member 1
CYP11B1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 55kDa
Affinity purification
Cancer, Cell Cycle, Growth Factors, Signal Transduction
P15538
Optimal dilutions for each application to be determined by the researcher.