anti-AMPK alpha-1 (human) Rabbit Monoclonal (RM301)
Product Code:
REV-31-1186-00
Antibody Isotype:
Rabbit IgG
Antibody Clonality:
Recombinant Antibody
Applications:- Immunohistochemistry (IHC)
- Western Blot (WB)
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This product comes from:
Switzerland.
Typical lead time:
14-21 working days.
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Further Information
Alternate Names/Synonyms:
AMPKA1; 5'-AMP-activated Protein Kinase Catalytic Subunit alpha-1
N/A
32160000
liquid
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Avoid freeze/thaw cycles.
A peptide corresponding to the residues near the C-terminus of human AMPK alpha-1.
Recombinant Antibody. This antibody reacts to human AMPK alpha-1 (AMPKA1) (5'-AMP-activated protein kinase catalytic subunit alpha-1). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic alpha subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms ( alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations able to form complexes. The catalytic alpha subunit of AMPK is activated allosterically by AMP, and by phosphorylation via the AMPK kinases LKB1 and CaMKK beta. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK?s role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity and diabetes. 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK alpha 1) belongs to the serine/threonine protein kinase family and is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK).
Q13131
Vial
AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic alpha subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms ( alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations able to form complexes. The catalytic alpha subunit of AMPK is activated allosterically by AMP, and by phosphorylation via the AMPK kinases LKB1 and CaMKK beta. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK?s role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity and diabetes. 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK alpha 1) belongs to the serine/threonine protein kinase family and is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK).
Protein A purified.
Rabbit
This antibody reacts to human AMPK alpha-1 (AMPKA1) (5'-AMP-activated protein kinase catalytic subunit alpha-1).
Non-hazardous
Primary Antibodies
12352203
Stable for at least 1 year after receipt when stored at -20°C.