anti-Phospho-Rsk1 (Thr359/Ser363) (human) Rabbit Monoclonal (RM233)
Product Code:
REV-31-1117-00
Antibody Isotype:
Rabbit IgG
Antibody Clonality:
Recombinant Antibody
Applications:- Immunohistochemistry (IHC)
- Western Blot (WB)
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This product comes from:
Switzerland.
Typical lead time:
14-21 working days.
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Further Information
Alternate Names/Synonyms:
Ribosomal Protein S6 Kinase alpha-1; S6K-alpha-1; MAPKAPK-1a;
N/A
32160000
liquid
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Avoid freeze/thaw cycles.
A phospho-peptide corresponding to human phospho-Rsk1 (Thr359/Ser363).
Recombinant Antibody. This antibody reacts to human RSK1 only when phosphorylated at Thr359/Ser363. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363 and Thr573, are important for kinase activation. RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters. Evidence from animal models suggests that RSK1 is a key regulator of glucose homeostasis and cell size.
Q15418
Vial
The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363 and Thr573, are important for kinase activation. RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters. Evidence from animal models suggests that RSK1 is a key regulator of glucose homeostasis and cell size.
Protein A purified.
Rabbit
This antibody reacts to human RSK1 only when phosphorylated at Thr359/Ser363.
Non-hazardous
Primary Antibodies
12352203
Stable for at least 1 year after receipt when stored at -20°C.