ProSci

Alirocumab (PCSK9) Antibody, Monoclonal

Product Code:
 
PSI-10-485
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Antibody Isotype:
 
IgG1-kappa
Antibody Clonality:
 
Recombinant Antibody
Regulatory Status:
 
RUO
Shipping:
 
blue ice
Storage:
 
Store at -80˚C
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PSI-10-485-0.1mg0.1mg£657.00
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This product comes from: United States.
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Further Information

Additional Names:
REGN727,SAR-236553,
Background:
Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of diet and statin treatment. It is a human monoclonal antibody part of the family of the PCSK9 inhibitors which are a novel class of anticholesterol therapeutics. From this family, it was the first agent to receive FDA approval. The FDA approval was contingent on the completion of further clinical trials to better determine efficacy and safety. PCSK9 inhibition facilitates more LDL-C clearance from the blood.
Buffer:
PBS buffer pH7.5
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Homo sapiens / PCSK9 [Homo sapiens]
NCBI Organism:
homo sapiens
Purification:
>95%
Research Area:
Drug Analogues
Source:
CHO cells
User NOte:
Optimal dilutions for each application to be determined by the researcher.