anti-April (mouse), mAb (blocking) (Centotto-1) (preservative free)
Product Code:
AG-20B-0083PF
Antibody Isotype:
Mouse IgG1kappa
Antibody Clonality:
Monoclonal
Antibody Clone:
Centotto-1
Applications:- Blocking
- Immunoprecipitation (IP)
Storage:
Short Term: +4°C, Long Term: -20°C
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This product comes from:
Switzerland.
Typical lead time:
7-10 working days.
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Further Information
Alternate Names/Synonyms:
A Proliferation Inducing Ligand; Tumor Necrosis Factor Ligand Superfamily Member 13; TNFSF13; TALL-2; CD256
1mg/ml
32160000
<0.01EU/µg purified protein (LAL test).
liquid
Liquid. In PBS.
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Recombinant mouse APRIL.
Preservative Free
Monoclonal Antibody. Recognizes mouse recombinant and endogenous APRIL. Applications: FUNC (Blocking), IP. Clone: Centotto-1. Isotype: Mouse IgG1kappa. Liquid. In PBS. APRIL is a secreted cytokine, belonging to the TNF superfamily that binds to transmembrane activator and CAML interactor (TACI), B cell maturation antigen (BCMA) and can interact with carbohydrate side chains of heparan sulfate proteoglycans (HSPG) that may trigger cross-linking. APRIL maintains B cell homeostasis by acting at a later stage, modulating the function and survival of antigen-experienced B cells. APRIL (as well as BAFF) stimulates class-switch recombination (CSR), hence contributes to shaping humoral effector mechanisms. With regards to humoral memory, APRIL is involved in the establishment and survival of the long-lived plasma cell (LLPC) pool in the bone marrow (BM). Recently, APRIL has been shown to confer atheroprotection via binding to heparan sulfate (HS) chains of heparan-sulfate proteoglycan 2 (HSPG2), which limits LDL retention, macrophage accumulation and necrotic core formation.
Q9D777
Plastic Vial
APRIL is a secreted cytokine, belonging to the TNF superfamily that binds to transmembrane activator and CAML interactor (TACI), B cell maturation antigen (BCMA) and can interact with carbohydrate side chains of heparan sulfate proteoglycans (HSPG) that may trigger cross-linking. APRIL maintains B cell homeostasis by acting at a later stage, modulating the function and survival of antigen-experienced B cells. APRIL (as well as BAFF) stimulates class-switch recombination (CSR), hence contributes to shaping humoral effector mechanisms. With regards to humoral memory, APRIL is involved in the establishment and survival of the long-lived plasma cell (LLPC) pool in the bone marrow (BM). Recently, APRIL has been shown to confer atheroprotection via binding to heparan sulfate (HS) chains of heparan-sulfate proteoglycan 2 (HSPG2), which limits LDL retention,macrophage accumulation and necrotic core formation.
>95% (SDS-PAGE)
Purified from concentrated hybridoma tissue culture supernatant.
Recognizes mouse recombinant and endogenous APRIL.
Non-hazardous
Primary Antibodies
12352203
Stable for at least 1 year after receipt when stored at -20°C.