NSJ Bioreagents

P-Glycoprotein Antibody

Product Code:
 
NSJ-F49437
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the P-Glycoprotein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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P-Glycoprotein antibody western blot analysis in K562 lysate
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P-Glycoprotein antibody western blot analysis in K562 lysate

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CodeSizePrice
NSJ-F49437-0.08ML0.08 ml£260.00
Quantity:
NSJ-F49437-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the P-Glycoprotein antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 647-677 from the human protein was used as the immunogen for this P-Glycoprotein antibody.
Limitation:
This P-Glycoprotein antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P08183