NSJ Bioreagents

ApoE Antibody (Apolipoprotein E)

Product Code:
 
NSJ-F50536
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Aliquot the ApoE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot analysis of lysate from human plasma tissue lysate using ApoE antibody diluted at 1:1000. Predicted molecular weight: 34-37 kDa~
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IHC analysis of FFPE human hepatocarcinoma tissue stained with ApoE antibody
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Western blot analysis of lysate from human plasma tissue lysate using ApoE antibody diluted at 1:1000. Predicted molecular weight: 34-37 kDa~
IHC analysis of FFPE human hepatocarcinoma tissue stained with ApoE antibody

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CodeSizePrice
NSJ-F50536-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50536-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the ApoE antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 263-292 from the human protein was used as the immunogen for this ApoE antibody.
Limitation:
This ApoE antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Species Reactivity (Predicted):
Primate, Rabbit
Uniprot #:
P02649