NSJ Bioreagents

Phospho-Raptor Antibody (pS863)

Product Code:
 
NSJ-F48549
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Dot Blot
  • Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Aliquot the phospho-Raptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Dot blot analysis of phospho-Raptor antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.
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Dot blot analysis of phospho-Raptor antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.

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CodeSizePrice
NSJ-F48549-0.08ML0.08 ml£260.00
Quantity:
NSJ-F48549-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
Dot blot: 1:500
Application Note:
Titration of the phospho-Raptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC). It plays a pivotal role as a scaffold protein in the FRAP1-signaling pathway and this interaction is essential for the catalyzed phosphorylation of EIF4EBP1. It has a positive role in nutrient-stimulated signaling to the downstream effector RPS6KB1. Under nutrient-deprived conditions, raptor serves as a negative regulator of FRAP1 kinase activity. Regulation of the interaction with FRAP1 is a critical mechanism by which cells coordinate the rate of cell growth and maintenance of cell size with different environmental conditions.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This phospho-Raptor antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS863 of human Raptor.
Limitation:
This phospho-Raptor antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q8N122