TargetMol

Taccalonolide B

Product Code:
 
TAR-TN2256
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TN2256-25mg25mgEnquire
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TAR-TN2256-50mg50mgEnquire
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TAR-TN2256-1mg1mg£109.00
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TAR-TN2256-5mg5mg£165.00
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TAR-TN2256-10mg10mg£230.00
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  • Further Information
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Further Information

Bioactivity:
Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.
CAS:
108885-69-4
Formula:
C34H44O13
Molecular Weight:
660.713
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
[H][C@@]12[C@H](O)[C@@]3([H])[C@]4([H])[C@@H](O)C(=O)[C@@]5([H])C[C@@H]6O[C@@H]6[C@H](OC(C)=O)[C@]5(C)[C@@]4([H])[C@H](OC(C)=O)[C@H](OC(C)=O)[C@]3(C)[C@@]1([H])[C@H](C)C=C1OC(=O)[C@@](C)(O)[C@]21C
Target:
Microtubule Associated

Documents

References

Potent Taccalonolides, AF and AJ, Inform Significant Structure??Activity Relationships and Tubulin as the Binding Site of These Microtubule StabilizersJ. Am. Chem. Soc., 2011, 133 (47), pp 19064??19067