TargetMol

SAR125844

Product Code:
 
TAR-T5467
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5467-1mg1mg£95.00
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TAR-T5467-2mg2mg£106.00
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TAR-T5467-5mg5mg£128.00
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TAR-T5467-1mL1 mL * 10 mM (in DMSO)£141.00
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TAR-T5467-10mg10mg£165.00
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TAR-T5467-25mg25mg£262.00
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TAR-T5467-50mg50mg£378.00
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TAR-T5467-100mg100mg£570.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)
CAS:
1116743-46-4
Formula:
C25H23FN8O2S2
Molecular Weight:
550.63
Pathway:
Tyrosine Kinase/Adaptors; Apoptosis
Purity:
0.9839
SMILES:
Fc1ccc(cc1)-c1ccc2nnc(Sc3ccc4nc(NC(=O)NCCN5CCOCC5)sc4c3)n2n1
Target:
Apoptosis; c-Met/HGFR

Documents

References

Egile C, et al. The selective intravenous inhibitor of the MET tyrosine kinase SAR125844 inhibits tumor growth in MET-amplified cancer. Mol Cancer Ther. 2015 Feb;14(2):384-94.