TargetMol

CM026

Product Code:
 
TAR-T23901
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T23901-100mg100mgEnquire
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Further Information

Bioactivity:
CM026 is a selective aldehyde dehydrogenase 1A1 inhibitor that acts by binding within the aldehyde binding pocket of ALDH1A1 in an uncompetitive partial mode of inhibition.
CAS:
851941-94-1
Formula:
C22H30N6O4
Molecular Weight:
442.52
Purity:
0.98
SMILES:
CC(C)CCn1c(CN2CCN(CC2)C(=O)c2ccoc2)nc2n(C)c(=O)n(C)c(=O)c12

Documents

References

1. Morgan CA, Hurley TD. Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors. J Med Chem. 2015 Feb 26;58(4):1964-75. doi: 10.1021/jm501900s. Epub 2015 Feb 10. PubMed PMID: 25634381; PubMed Central PMCID: PMC4344389.