Rohitukin

Product Code:

TAR-T26115

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

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Code	Size	Price

TAR-T26115-25mg

25mg

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Further Information

Bioactivity:

Rohitukin is a chromane alkaloid and a precursor of flavopiridol, a hopeful anti-cancer compound.

CAS:

62653-92-3

Formula:

C34H42O13

Molecular Weight:

658.697

Purity:

0.98

SMILES:

[H][C@]12CC(=O)OC[C@]1(C)OC(=O)C[C@H](OC(C)=O)[C@]2(C)[C@H]1[C@H](OC=O)[C@@H](OC(=O)CC(C)C)[C@@]2(C)[C@@H](CC(=O)[C@]2(O)C1=C)c1ccoc1

Documents

References

1. Sarker SD, Savchenko T, Whiting P, Sik V, Dinan L. Two limonoids from Turraea obtusifolia (Meliaceae), prieurianin and rohitukin, antagonise 20-hydroxyecdysone action in a Drosophila cell line. Arch Insect Biochem Physiol. 1997;35(1-2):211-7. PubMed PMID: 9131785. 2. Dzoyem JP, Tsamo AT, Melong R, Mkounga P, Nkengfack AE, McGaw LJ, Eloff JN. Cytotoxicity, nitric oxide and acetylcholinesterase inhibitory activity of three limonoids isolated from Trichilia welwitschii (Meliaceae). Biol Res. 2015 Oct 13;48:57. doi: 10.1186/s40659-015-0049-0. PubMed PMID: 26463660; PubMed Central PMCID: PMC4604621. 3. Mohanakumara P, Sreejayan N, Priti V, Ramesha BT, Ravikanth G, Ganeshaiah KN, Vasudeva R, Mohan J, Santhoshkumar TR, Mishra PD, Ram V, Shaanker RU. Dysoxylum binectariferum Hook.f (Meliaceae), a rich source of rohitukine. Fitoterapia. 2010 Mar;81(2):145-8. doi: 10.1016/j.fitote.2009.08.010. Epub 2009 Aug 15. PubMed PMID: 19686817. 4. Polonsky J, Varon Z, Marazano C, Arnoux B, Pettit GR, Schmid JM, Ochi M, Kotsuki H. The structure of amoorastatone and the cytotoxic limonoid 12-hydroxyamoorastatin. Experientia. 1979 Aug 15;35(8):987-9. PubMed PMID: 477905.