TargetMol

RS 15385-197

Product Code:
 
TAR-T26134
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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  • Further Information
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Further Information

Bioactivity:
RS 15385-197 is a selective alpha 2-adrenoceptor antagonist.
CAS:
119813-87-5
Formula:
C18H26N2O3S
Molecular Weight:
350.48
Purity:
0.98
SMILES:
[H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(C)(=O)=O

Documents

References

1. Tallentire D, McRae G, Spedding M, Clark R, Vickery B. Modulation of sexual behaviour in the rat by a potent and selective alpha 2-adrenoceptor antagonist, delequamine (RS-15385-197). Br J Pharmacol. 1996 May;118(1):63-72. PubMed PMID: 8733577; PubMed Central PMCID: PMC1909492. 2. Brown CM, MacKinnon AC, Redfern WS, Hicks PE, Kilpatrick AT, Small C, Ramcharan M, Clague RU, Clark RD, MacFarlane CB, et al. The pharmacology of RS-15385-197, a potent and selective alpha 2-adrenoceptor antagonist. Br J Pharmacol. 1993 Feb;108(2):516-25. PubMed PMID: 8095420; PubMed Central PMCID: PMC1908001. 3. Hume SP, Hirani E, Opacka-Juffry J, Osman S, Myers R, Gunn RN, McCarron JA, Clark RD, Melichar J, Nutt DJ, Pike VW. Evaluation of [O-methyl-11C]RS-15385-197 as a positron emission tomography radioligand for central alpha2-adrenoceptors. Eur J Nucl Med. 2000 May;27(5):475-84. PubMed PMID: 10853800. 4. MacKinnon AC, Kilpatrick AT, Kenny BA, Spedding M, Brown CM. [3H]-RS-15385-197, a selective and high affinity radioligand for alpha 2-adrenoceptors: implications for receptor classification. Br J Pharmacol. 1992 Aug;106(4):1011-8. PubMed PMID: 1327384; PubMed Central PMCID: PMC1907641.