TargetMol

RS 2135

Product Code:
 
TAR-T26136
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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  • Further Information
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Further Information

Bioactivity:
RS 2135 is a novel class I antiarrhythmic agent to inhibit ischemia-induced ventricular arrhythmias.
CAS:
133775-36-7
Formula:
C18H21ClN2O2
Molecular Weight:
332.83
Purity:
0.98
SMILES:
Cl.[H][C@@]12CCC[C@@]3([H])[C@H](N)Cc4c(n(C(=O)C1)c1cccc(O)c41)[C@@]23[H]

Documents

References

1. Yorikane R, Sada T, Koike H. Electrophysiologic effects of RS-2135, a new antiarrhythmic compound, on canine Purkinje fibers. J Cardiovasc Pharmacol. 1992 Dec;20(6):955-60. PubMed PMID: 1282599. 2. Yorikane R, Mizuno H, Itoh Y, Miyake S, Koike H. Effects of RS-2135, a novel class I antiarrhythmic agent, on sustained ventricular tachycardia after coronary embolization in conscious dogs. J Cardiovasc Pharmacol. 1994 Jul;24(1):28-36. PubMed PMID: 7521486. 3. Yorikane R, Sada T, Koike H. Effects of RS-2135, a new antiarrhythmic agent, on the kinetics of use-dependent decrease in maximum upstroke velocity in guinea pig ventricular myocardium. J Cardiovasc Pharmacol. 1993 Mar;21(3):430-4. PubMed PMID: 7681504. 4. Ito K, Nagafuchi K, Taga A, Yorikane R, Koike H. Possible involvement of altered Na+ -Ca2+ exchange in negative inotropic effects of class I antiarrhythmic drugs on rabbit and rat ventricles. J Cardiovasc Pharmacol. 1996 Mar;27(3):355-61. PubMed PMID: 8907796.