Cassaine

Product Code:

TAR-T30757

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

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Code	Size	Price

TAR-T30757-25mg

25mg

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Further Information

Bioactivity:

Cassaine is an erythrophleum alkaloid.

CAS:

468-76-8

Formula:

C24H39NO4

Molecular Weight:

405.579

Purity:

0.98

SMILES:

[H][C@]12CCC(=C/C(=O)OCCN(C)C)[C@H](C)[C@]1([H])C(=O)C[C@@]1([H])C(C)(C)[C@@H](O)CC[C@]21C

Documents

References

1. Ha MT, Tran MH, Phuong TT, Kim JA, Woo MH, Choi JS, Lee S, Lee JH, Lee HK, Min BS. Cytotoxic and apoptosis-inducing activities against human lung cancer cell lines of cassaine diterpenoids from the bark of Erythrophleum fordii. Bioorg Med Chem Lett. 2017 Jul 1;27(13):2946-2952. doi: 10.1016/j.bmcl.2017.05.006. Epub 2017 May 4. PubMed PMID: 28506750. 2. Hung TM, Cuong TD, Kim JA, Tae N, Lee JH, Min BS. Cassaine diterpene alkaloids from Erythrophleum fordii and their anti-angiogenic effect. Bioorg Med Chem Lett. 2014 Jan 1;24(1):168-72. doi: 10.1016/j.bmcl.2013.11.048. Epub 2013 Nov 27. PubMed PMID: 24332631. 3. Ravindar K, Caron PY, Deslongchamps P. Anionic polycyclization entry to tricycles related to quassinoids and terpenoids: a stereocontrolled total synthesis of (+)-cassaine. J Org Chem. 2014 Sep 5;79(17):7979-99. doi: 10.1021/jo501122k. Epub 2014 Aug 7. PubMed PMID: 25057897. 4. Hung TM, Cuong TD, Kim JA, Lee JH, Woo MH, Min BS. In vitro apoptotic effect of cassaine-type diterpene amides from Erythrophleum fordii on PC-3 prostate cancer cells. Bioorg Med Chem Lett. 2014 Nov 1;24(21):4989-94. doi: 10.1016/j.bmcl.2014.09.025. Epub 2014 Sep 16. PubMed PMID: 25278231.